个人简介
金沙9170登录线路教授,博士生导师;主要从事生物传感分析、核酸纳米技术、生物医学材料等研究。致力于开发新型分析检测方法与探针、开发先进纳米技术与材料、建立智能医学诊疗材料与方法。截至目前,在相关领域国际权威学术期刊发表论文160余篇(包括62篇通讯作者论文和20篇一作论文),一作及通讯作者论文包括1篇Chem. Rev.,1篇Matter,5篇J. Am. Chem. Soc.,9篇Angew. Chem. Int. Ed.,3篇ACS Nano,1篇Nano lett.,2篇CCS Chem.,1篇Nucleic Acids Res.,2篇Adv. Mater.,11篇Chem. Sci.,6篇Small,12篇Anal. Chem.等。主持国家自然科学基金4项,申请并获批美国及中国专利各两项,参与编写关于核酸纳米机器和核酸信号扩增反应的书目章节四个。荣获湖北省化学化工青年创新奖。
教育经历
1999.09-2003.07 郑州大学化学系 大学本科
2003.09-2009.01 中科院长春应化所 博士研究生
工作经历
2009.02-014.06 耶路撒冷希伯来大学 博士后
2014.07-至今 金沙9170登录线路 教授、博导
研究方向
生物分析与传感、核酸化学生物学、核酸纳米技术
代表成果
1. Shizhen He, Shanshan Yu, Ruomeng Li, Yingying Chen, Qing Wang, Yuqiu He, Xiaoqing Liu, Fuan Wang*, On-Site Nonenzymatic Orthogonal Activation of a Catalytic DNA Circuit for Self-Reinforced In Vivo MicroRNA Imaging. Angew. Chem. Int. Ed., 2022, 61, e202206529. (VIP PAPER)
2. Huimin Wang, Yuqiu He, Jie Wei, Hong Wang, Kang Ma, Yangjie Zhou, Xiaoqing Liu, Xiang Zhou, Fuan Wang*, Construction of an Autocatalytic Hybridization Assembly Circuit for Amplified In Vivo MicroRNA Imaging. Angew. Chem. Int. Ed., 2022, 61, e202115489. (HOT PAPER)
3. Qing Wang, Kaiyue Tan, Hong Wang, Jinhua Shang, Yeqing Wan, Xiaoqing Liu, Xiaocheng Weng, Fuan Wang*, Orthogonal Demethylase-Activated Deoxyribozyme for Intracellular Imaging and Gene Regulation. J. Am. Chem. Soc., 2021, 143, 6895.
4. Jing Wang, Shanshan Yu, Qiong Wu, Xue Gong, Shizhen He, Jinhua Shang, Xiaoqing Liu, Fuan Wang*, A Self-Catabolic Multifunctional DNAzyme Nanosponge for Programmable Drug Delivery and Efficient Gene Silencing. Angew. Chem. Int. Ed., 2021, 60, 10766.
5. Xue Gong, Ruomeng Li, Jing Wang, Jie Wei, Kang Ma, Xiaoqing Liu, Fuan Wang*, A Smart Theranostic Nanocapsule for Spatiotemporally Programmable Photo-Genetherapy. Angew. Chem. Int. Ed., 2020, 59, 21648.
6. Jie Wei, Huimin Wang, Qiong Wu, Xue Gong, Kang Ma, Xiaoqing Liu and Fuan Wang*, A Smart Autocatalytic DNAzyme Biocircuit for in vivo MRI-Guided MicroRNA Imaging. Angew. Chem. Int. Ed., 2020, 59, 5965. (HIGHLY CITED PAPER, HOT PAPER)
7. Huimin Wang, Yuqi Chen, Hong Wang, Xiaoqing Liu, Xiang Zhou, Fuan Wang*, DNAzyme-Loading MOFs for Self-Sufficient Gene Therapy. Angew. Chem. Int. Ed., 2019, 58, 7380. (HIGHLY CITED PAPER)
8. Xue Gong, Haizhou Wang, Ruomeng Li, Kaiyue Tan, Jie Wei, Jing Wang, Chen Hong, Jinhua Shang, Xiaoqing Liu*, Jing Liu, Fuan Wang*, A Smart Multiantenna Gene Theranostic System Based on the Programmed Assembly of Hypoxia-Related siRNAs. Nat. Commun., 2021, 12, 3953.
9. Junlin Sun, Feng Liu, Wenqian Yu, Dandan Fu, Qunying Jiang, Fengye Mo, Xiuyuan Wang, Tianhui Shi, Fuan Wang*, Dai-Wen Pang*, Xiaoqing Liu*, Visualization of Vaccine Dynamics with Quantum Dots for Immunotherapy. Angew. Chem. Int. Ed., 2021, 60, 24275.
10. Wenqian Yu, Junlin Sun, Xiuyuan Wang, Shuyi Yu, Mingzhu Yan, Fuan Wang*, Xiaoqing Liu*, Boosting Cancer Immunotherapy via the Convenient A2AR Inhibition Using a Tunable Nanocatalyst with Light-Enhanced Activity. Adv. Mater. 2022, 34, 2106967.